Evaluation of Analytical Performance of Rapid Diagnostic Test Kits for Blood Groupings
DOI:
https://doi.org/10.26437/ajar.v10i2.808Keywords:
Blood group.detection. performance. rapid diagnostic test. rhesus factor.Abstract
Purpose: This study aimed to determine the analytical performance of ABO and Rh D rapid diagnostic test kits as a substitute for the conventional tube method.
Design/Methodology/Approach: 161 participants who visited the Koforidua Technical University Clinic Laboratory were recruited from August to September 2022. The rapid diagnostic ABO and Rh D test kits were used to determine the ABO and Rh D blood groups of the study participants. The concordance rate, kappa analysis and Receiver Operating Characteristics (ROC) were performed.
Findings: The strength of agreement of the two diagnostic methods in detecting ABO and Rh D blood type using Kappa analyses was excellent (k꞊1.00; standard error꞊0.00; P-value=0.001). All diagnostic performance statistics of the RDT were not different from the tube method being the standard.
Research Limitation: This research focused on the analytical performance of the rapid test kits but not on different brands of the test kits for their comparative studies.
Practical Implication: This paper could potentially ensure reliable results, facilitate certification, and enable test kits to be accepted in the market.
Social Implication: This study will assist policy-makers in increasing access to healthcare to enable testing in resource-limited settings and improving health outcomes as timely diagnosis and management facilitate better patient outcomes.
Originality/ Value: This study is based on providing reliable information on portable and point-of-care diagnostic testing outside conventional laboratory settings for timely diagnosis.
References
Armstrong, B. (2008d). Benefits and risks of transfusion. ISBT Science Series, 3(2), 216–230.
https://doi.org/10.1111/J.1751-2824.2008.00199.X
Bahati, F., Mcknight, J., Swaleh, F., Malaba, R., Karimi, L., Ramadhan, M., Kibet Kiptim, P.,
Okiro, E. A., & English, M. (2022). Reporting of diagnostic and laboratory tests by general hospitals as an indication of access to diagnostic laboratory services in Kenya. PLoS ONE, 17(4 April). https://doi.org/10.1371/JOURNAL.PONE.0266667
Chapman, J. F., Elliott, C., Knowles, S. M., Milkins, C. E., Poole, G. D., Duguid, J., Boulton, F.,
McClelland, B., Smith, N., Cohen, H., Rowley, M., & Taylor, J. (2004). Guidelines for compatibility procedures in blood transfusion laboratories. Transfusion Medicine, 14(1), 59–73. https://doi.org/10.1111/J.0958-7578.2004.00482.X
Engel, N., & Krumeich, A. (2020). Valuing Simplicity: Developing a Good Point of Care
Diagnostic. Frontiers in Sociology, 5. https://doi.org/10.3389/FSOC.2020.00037/FULL
Li, H. Y., & Guo, K. (2022a). Blood Group Testing. Frontiers in Medicine, 9.
https://doi.org/10.3389/FMED.2022.827619/FULL
Li, H. Y., & Guo, K. (2022b). Blood Group Testing. Frontiers in Medicine, 9.
https://doi.org/10.3389/FMED.2022.827619/FULL
Li, H. Y., & Guo, K. (2022c). Blood Group Testing. Frontiers in Medicine, 9.
https://doi.org/10.3389/FMED.2022.827619/FULL
Li, J., & Guo, X. (2024). Rapid ABO and Rh D blood group typing using dielectrophoretic
characterization of red blood cells. International Journal of Hematology, 42(4), 210-218.
Li, J., Zhang, P., Chen, S., & Liu, Y. (2023). Paper-based diagnostic device for rapid ABO and Rh
blood typing: A point-of-care alternative. Journal of Medical Diagnostics, 45(1), 34-42. Li, J., Zhang, P., Chen, S., & Liu, Y. (2024). Optical sensor-based ABO and Rh D blood group
typing: Recent advances. Biomedical Optics Express, 12(2), 152-161.
Magnette, A., Chatelain, B., & Ten Cate, H. (2024). ABO and Rh D blood typing: Comparison
between rapid diagnostic tests and the conventional tube method. Journal of Blood Transfusion, 48(2), 200-210.
Pandey, P., Shah, M., & Chauhan, V. (2024). Advances in rapid diagnostic testing for blood group
typing: A review of current methods. Clinical Diagnostic Hematology, 31(1), 15-23.
Perel, P., Clayton, T., Altman, D. G., Croft, P., Douglas, I., Hemingway, H., Hingorani,
A., Morley, K. I., Riley, R., Timmis, A., van der Windt, D., & Roberts, I. (2014). Red Blood Cell Transfusion and Mortality in Trauma Patients: Risk-Stratified Analysis of an Observational Study. PLoS Medicine, 11(6), 1–9. https://doi.org/10.1371/JOURNAL.PMED.1001664
Reynolds, V., Van Buren, N. L., & Gorlin, J. B. (2023). Confronting the challenge of gender
nonconforming donors: a blood center's three‐year experience. Transfusion, 63(7), 1284-1289.
Songjaroen, T., Primpray, V., Manosarn, T., Khumchanta, W., Sakuldamrongpanich, T.,
Kulkeratiyut, S., & Laiwattanapaisal, W. (2018). A simple and low-cost portable paper-based ABO blood typing device for point-of-care testing. Journal of Immunoassay and Immunochemistry, 39(3), 292–307. https://doi.org/10.1080/15321819.2018.1486856
Srivathsa, M., & Dendukuri, N. (2023). Automated ABO Rh-D blood typing using smartphone
imaging and fabric strip diagnostics. Journal of Blood Group Serology, 29(3), 112-119.
Then, X., Tan, J., & Choo, C. (2023). Evaluation of paper-based diagnostics for ABO and Rh D
blood typing: A comparative study. Sensors and Diagnostics, 58(5), 85-94.
Van Buren, C., & Gorlin, J. (2023). Diagnostic performance of rapid diagnostic test kits in ABO
and Rh D blood typing: A multi-center assessment. Transfusion Medicine Reviews, 67(1), 99-105.
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